Email 610: Side Effects of Co-trimoxazole

Posted by Pozziepinoy on 9:10 AM

Hi guys who has bad experience on Cotrimoxazole? Have you experienced white patches inside you mouth? And rashes on your skin ( red rashes very painful and itchy) what did your doctor advise to you? Tnx

POZZIEPINOY'S RESPONSE

Hi there.

Thank you for your email.

Everyone's reaction to a medicine is different. It is difficult to predict which side-effects you will have from taking a particular medicine, or whether you will have any side-effects at all. The important thing is to tell your HIV doctor if you are having problems with your medicine. In your case, since you think you are getting some symptoms, which may or may not be related to co-trimoxazole, it is best for you to go back to your hubs and get a consultation.

For the benefit of everyone, I made a research on the side effects of co-trimoxazole:


Along with its needed effects, co-trimoxazole (sulfamethoxazole / trimethoprim) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking sulfamethoxazole / trimethoprim:
Rare
  • Abdominal or stomach pain
  • black, tarry stools
  • blistering, peeling, or loosening of the skin
  • changes in skin color
  • chest pain
  • chills
  • cough or hoarseness
  • dark urine
  • diarrhea
  • dizziness
  • fever with or without chills
  • general feeling of tiredness or weakness
  • headache
  • itching
  • joint or muscle pain
  • light-colored stools
  • loss of appetite
  • lower back or side pain
  • nausea
  • pain, tenderness, or swelling of the foot or leg
  • painful or difficult urination
  • pale skin
  • rash
  • red irritated eyes
  • red skin lesions, often with a purple center
  • shortness of breath
  • sore throat
  • sores, ulcers, or white spots in the mouth or on the lips
  • swollen or painful glands
  • tightness in the chest
  • unpleasant breath odor
  • unusual bleeding or bruising
  • vomiting of blood
  • wheezing
  • yellow eyes or skin
Incidence not known
  • Abdominal or stomach tenderness
  • back, leg, or stomach pains
  • bleeding gums
  • blindness or vision changes
  • blisters, hives, or itching
  • bloating
  • blood in the urine or stools
  • bluish-colored lips, fingernails, or palms
  • burning, crawling, itching, numbness, painful, prickling, "pins and needles", or tingling feelings
  • burning of the face or mouth
  • chest pain
  • cloudy urine
  • confusion
  • constipation
  • continuing ringing or buzzing or other unexplained noise in the ears
  • convulsions
  • cracks in the skin
  • decreased frequency or amount of urine
  • diarrhea, watery and severe, which may also be bloody
  • difficulty with breathing
  • difficulty with swallowing
  • fainting spells
  • general body swelling
  • general feeling of discomfort or illness
  • hair loss
  • hearing loss
  • hives
  • increased blood pressure
  • increased thirst
  • indigestion
  • irregular heartbeat
  • large, flat, blue, or purplish patches in the skin
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • loss of heat from the body
  • muscle or joint pain
  • nosebleeds
  • not able to pass urine
  • numbness or tingling in the hands, feet, or lips
  • pain or burning while urinating
  • pinpoint red spots on the skin
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • raised red swellings on the skin, the buttocks, legs, or ankles
  • redness of the white part of the eyes
  • redness, swelling, or soreness of the tongue
  • sores, ulcers, or white spots on the lips or in the mouth
  • soreness of the muscles
  • stiff neck or back
  • swelling of the face, hands, legs, and feet
  • unsteadiness, trembling, or other problems with muscle control or coordination
  • unusual weight loss
  • weakness in the hands or feet
  • weakness or heaviness of the legs
  • weight gain
Some side effects of sulfamethoxazole / trimethoprim may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
  • Passing of gas
Incidence not known
  • Discouragement
  • feeling of constant movement of self or surroundings
  • feeling sad or empty
  • increased sensitivity of skin to sunlight
  • irritability
  • lack of feeling or emotion
  • loss of interest or pleasure
  • nervousness
  • redness or other discoloration of the skin
  • seeing, hearing, or feeling things that are not there
  • sensation of spinning
  • severe sunburn
  • sleeplessness
  • trouble concentrating
  • trouble sleeping
  • unable to sleep
  • uncaring
  • weight loss





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